Comprehensive characterization of human genome variation by high coverage whole-genome sequencing of forty four Caucasians.

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Shen, Hui; Li, Jian; Zhang, Jigang; Xu, Chao; Jiang, Yan; Wu, Zikai; Zhao, Fuping; Liao, Li; Chen, Jun; Lin, Yong; Tian, Qing; Papasian, Christopher J.; Deng, Hong-Wen;
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 8,issue 4 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1371/journal.pone.0059494, pmc: PMC3618277
  • Subject: Computational Biology | Bio-Ontologies | Human Genetics | Population Genetics | Research Article | Biology | Genome Complexity | Medicine | Gene Ontologies | Genome Databases | Q | R | Genetics | Population Biology | Computer Science | Ontology and Logics | Science | Genome Analysis Tools | Genomics | Genome Sequencing | Genome-Wide Association Studies | Genetic Polymorphism | Sequence Assembly Tools

Whole genome sequencing studies are essential to obtain a comprehensive understanding of the vast pattern of human genomic variations. Here we report the results of a high-coverage whole genome sequencing study for 44 unrelated healthy Caucasian adults, each sequenced t... View more