Pinpointing Synaptic Loss Caused by Alzheimer’s Disease with fMRI

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Brickman, Adam M.; Small, Scott A.; Fleisher, Adam;
(2009)

During its earliest stage, before cell loss and independent of amyloid plaques and neurofibrillary tangles, Alzheimer's disease (AD) causes synaptic loss affecting the basal functional properties of neurons. In principle, synaptic loss can be detected by measuring AD-in... View more
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