The sustained release of basic fibroblast growth factor accelerates angiogenesis and the engraftment of the inactivated dermis by high hydrostatic pressure

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Le, Tien Minh; Morimoto, Naoki; Mitsui, Toshihito; Notodihardjo, Sharon Claudia; Munisso, Maria Chiara; Kakudo, Natsuko; Kusumoto, Kenji;
(2019)
  • Publisher: Public Library of Science
  • Journal: PLoS ONE, volume 14, issue 2 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Identifiers: doi: 10.1371/journal.pone.0208658, pmc: PMC6383993
  • Subject: Biotechnology | Research Article | Anatomy | Skin | Cardiovascular Physiology | Engineering and Technology | Dermis | Fibroblasts | Biological Tissue | Histology | Connective Tissue | Endocrine Physiology | Epidermis | Cellular Types | Surgical and Invasive Medical Procedures | Biology and Life Sciences | Growth Factors | Angiogenesis | Developmental Biology | Physiology | Medical Implants | Medicine | Integumentary System | Animal Cells | Plastic Surgery and Reconstructive Techniques | Medical Devices and Equipment | Connective Tissue Cells | Bioengineering | Q | R | Cell Biology | Science | Medicine and Health Sciences | Skin Grafting | Endocrinology

We developed a novel skin regeneration therapy combining nevus tissue inactivated by high hydrostatic pressure (HHP) in the reconstruction of the dermis with a cultured epidermal autograft (CEA). The issue with this treatment is the unstable survival of CEA on the inact... View more
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