Tumor Cells and Tumor-Associated Macrophages: Secreted Proteins as Potential Targets for Therapy

Article, Review English OPEN
Baay, Marc; Brouwer, Anja; Pauwels, Patrick; Peeters, Marc; Lardon, Filip;
(2011)
  • Publisher: Hindawi Publishing Corporation
  • Journal: Clinical and Developmental Immunology,volume 2,011 (issn: 1740-2522, eissn: 1740-2530)
  • Related identifiers: pmc: PMC3227419, doi: 10.1155/2011/565187
  • Subject: RC581-607 | Review Article | Immunologic diseases. Allergy | Article Subject

Inflammatory pathways, meant to defend the organism against infection and injury, as a byproduct, can promote an environment which favors tumor growth and metastasis. Tumor-associated macrophages (TAMs), which constitute a significant part of the tumor-infiltrating immu... View more
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