publication . Article . 2017

Selection bias and subject refusal in a cluster-randomized controlled trial

Barry Carter; Barcey Levy;
Open Access English
  • Published: 01 Jul 2017 Journal: BMC Medical Research Methodology (issn: 1471-2288, Copyright policy)
  • Publisher: BMC
Background Selection bias and non-participation bias are major methodological concerns which impact external validity. Cluster-randomized controlled trials are especially prone to selection bias as it is impractical to blind clusters to their allocation into intervention or control. This study assessed the impact of selection bias in a large cluster-randomized controlled trial. Methods The Improved Cardiovascular Risk Reduction to Enhance Rural Primary Care (ICARE) study examined the impact of a remote pharmacist-led intervention in twelve medical offices. To assess eligibility, a standardized form containing patient demographics and medical information was comp...
free text keywords: Selection bias, Non participation bias, Cluster randomized trial, Medicine (General), R5-920, Research Article, Health Informatics, Epidemiology
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34 references, page 1 of 3

Tripepi, G, Jager, KJ, Dekker, FW, Zoccali, C. Selection bias and information bias in clinical research. Nephron Clin Pract. 2010; 115 (2): c94-c99 [OpenAIRE] [PubMed] [DOI]

Hill, AM, McPhail, SM, Waldron, N, Etherton-Beer, C, Ingram, K, Flicker, L. Fall rates in hospital rehabilitation units after individualized patient and staff education programs: a pragmatic, stepped-wedge, cluster-randomized controlled trial. Lancet. 2015; 385 (9987): 2592-2599 [OpenAIRE] [PubMed] [DOI]

LaBresh, KA, Lazorick, S, Ariza, AJ, Furberg, RD, Whetstone, L, Hobbs, C. Implementation of the NHLBI integrated guidelines for cardiovascular health and risk reduction in children and adolescents: rationale and study design for young hearts, strong starts, a cluster-randomized trial targeting body mass index, blood pressure, and tobacco. Contemp Clin Trials. 2014; 37 (1): 98-105 [OpenAIRE] [PubMed] [DOI]

Eldridge, S, Ashby, D, Bennett, C, Wakelin, M, Feder, G. Internal and external validity of cluster-randomized trials: systematic review of recent trials. BMJ. 2008; 336 (7649): 876-880 [OpenAIRE] [PubMed] [DOI]

Torgerson, D. Contamination in trials: is cluster randomization the answer?. BMJ. 2001; 322 (7282): 355-357 [OpenAIRE] [PubMed] [DOI]

Gums, T, Carter, B, Foster, E. Cluster randomized trials for pharmacy practice research. Int J Clin Pharm. 2016; 38 (3): 607-614 [PubMed]

Eldridge, S, Kerry, S, Torgerson, D. Bias in identifying and recruiting participants in cluster randomized trials: what can be done?. BMJ. 2009; 339: b4006 [OpenAIRE] [PubMed] [DOI]

Brierley, G, Brabyn, S, Torgerson, D, Watson, J. Bias in recruitment to cluster randomized trials: a review of recent publications. J Eval Clin Pract. 2012; 18 (4): 878-886 [OpenAIRE] [PubMed] [DOI]

Giraudeau, B, Ravaud, P. Preventing bias in cluster randomized trials. PLoS Med. 2009; 6 (5): e1000065 [OpenAIRE] [PubMed] [DOI]

Campbell, MJ. Challenges of cluster randomized trials. J Comp Eff Res. 2014; 3 (3): 271-281 [OpenAIRE] [PubMed] [DOI]

Puffer, S, Torgerson, D, Watson, J. Evidence for risk of bias in cluster randomized trials: review of recent trials published in three general medical journals. BMJ. 2003; 327 (7418): 785-789 [OpenAIRE] [PubMed] [DOI]

Tol, WA, Komproe, IH, Susanty, D, Jordans, MJ, Macy, RD, De Jong, JT. School-based mental health intervention for children affected by political violence in Indonesia: a cluster randomized trial. JAMA. 2008; 300 (6): 655-662 [OpenAIRE] [PubMed] [DOI]

Campbell, R, Starkey, F, Holliday, J, Audrey, S, Bloor, M, Parry-Langdon, N. An informal school-based peer-led intervention for smoking prevention in adolescence (ASSIST): a cluster randomized trial. Lancet. 2008; 371 (9624): 1595-1602 [OpenAIRE] [PubMed] [DOI]

Jewkes, R, Nduna, M, Levin, J, Jama, N, Dunkle, K, Puren, A. Impact of Stepping Stones on incidence of HIV and HSV-2 and sexual behavior in rural South Africa: cluster randomized controlled trial. BMJ. 2008; 337: a506 [OpenAIRE] [PubMed] [DOI]

Davies, MJ, Heller, S, Skinner, TC, Campbell, MJ, Carey, ME, Cradock, S. Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) program for people with newly diagnosed type 2 diabetes: cluster randomized controlled trial. BMJ. 2008; 336 (7649): 491-495 [OpenAIRE] [PubMed] [DOI]

34 references, page 1 of 3
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