A chicory cytochrome P450 mono-oxygenase CYP71AV8 for the oxidation of (+)-valencene

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Cankar, K.; Houwelingen, van, A.M.M.L.; Bosch, H.J.; Sonke, Th.; Bouwmeester, H.J.; Beekwilder, M.J.;
  • Subject: artemisinin | functional-characterization | synthase | valencene | biosynthesis | yeast expression | nootkatone | cloning | sesquiterpenes

Chicory (Cichorium intybus L.), which is known to have a variety of terpene-hydroxylating activities, was screened for a P450 mono-oxygenase to convert (+)-valencene to (+)-nootkatone. A novel P450 cDNA was identified in a chicory root EST library. Co-expression of the ... View more
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