Role of Alveolar Macrophages in Chronic Obstructive Pulmonary Disease

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Vlahos, Ross; Bozinovski, Steven;
  • Publisher: Frontiers Media S.A.
  • Journal: Frontiers in Immunology,volume 5 (issn: 1664-3224, eissn: 1664-3224)
  • Related identifiers: pmc: PMC4160089, doi: 10.3389/fimmu.2014.00435
  • Subject: Review Article | alveolar macrophage | efferocytosis | Immunology | resolution | oxidative stress | chronic obstructive pulmonary disease | lung inflammation

Alveolar macrophages (AMs) represent a unique leukocyte population that responds to airborne irritants and microbes. This distinct microenvironment coordinates the maturation of long-lived AMs, which originate from fetal blood monocytes and self-renew through mechanisms... View more
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