Pathogenesis of Brain Edema and Investigation into Anti-Edema Drugs

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Michinaga, Shotaro; Koyama, Yutaka;
  • Publisher: MDPI AG
  • Journal: International Journal of Molecular Sciences, volume 16, issue 5, pages 9,949-9,975 (issn: 1422-0067, eissn: 1422-0067)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC4463627, doi: 10.3390/ijms16059949
  • Subject: blood-brain barrier | Chemistry | cold injury | QD1-999 | aquaporin | vasogenic edema | fluid percussion injury | QH301-705.5 | Review | vascular endothelial growth factor | ETB receptor | matrix metalloproteinase | cytotoxic edema | Biology (General)

Brain edema is a potentially fatal pathological state that occurs after brain injuries such as stroke and head trauma. In the edematous brain, excess accumulation of extracellular fluid results in elevation of intracranial pressure, leading to impaired nerve function. D... View more
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