Extrinsic and intrinsic factors controlling spermatogonial stem cell self-renewal and differentiation

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Mei, Xing-Xing; Wang, Jian; Wu, Ji;
  • Publisher: Wolters Kluwer Medknow Publications
  • Journal: Asian Journal of Andrology, volume 17, issue 3, pages 347-354 (issn: 1008-682X, eissn: 1745-7262)
  • Publisher copyright policies & self-archiving
  • Identifiers: doi: 10.4103/1008-682X.148080, pmc: PMC4430931
  • Subject: Diseases of the genitourinary system. Urology | RC870-923 | differentiation | spermatogonial stem cells | differentiation; self-renewal; signal; spermatogonial stem cells | Invited Review | self-renewal | signal
    mesheuropmc: endocrine system

Spermatogonial stem cells (SSCs), the stem cells responsible for male fertility, are one of a small number of cells with the abilities of both self-renewal and generation of large numbers of haploid cells. Technology improvements, most importantly, transplantation assay... View more
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