Effects of chronic fluoxetine treatment on neurogenesis and tryptophan hydroxylase expression in adolescent and adult rats

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Klomp, Anne; Václavů, Lena; Meerhoff, Gideon F.; Reneman, Liesbeth; Lucassen, Paul J.;
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 9,issue 5 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1371/journal.pone.0097603, pmc: PMC4020860
  • Subject: Cell Differentiation | Research Article | Molecular Cell Biology | Mental Health and Psychiatry | Psychology | Mental Health Therapies | Neurology | Cellular Types | Stem Cells | Biology and Life Sciences | Neural Stem Cells | Developmental Biology | Neuroscience | Neuropsychology | Animal Cells | Medicine | Cellular Neuroscience | Developmental and Pediatric Neurology | Q | R | Cell Biology | Science | Developmental Neuroscience | Medicine and Health Sciences | Drug Psychotherapy

The antidepressant drug fluoxetine (Prozac) has been increasingly prescribed to children and adolescents with depressive disorders despite a lack of thorough understanding of its therapeutic effects in the paediatric population and of its putative neurodevelopmental eff... View more
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