Characterization of a Single Chain Fv Antibody that Reacts with Free Morphine

Article, Other literature type English OPEN
Matsukizono, Miho ; Kamegawa, Mariko ; Tanaka, Koichi ; Kohra, Shinya ; Arizono, Koji ; Hamazoe, Yuta ; Sugimura, Kazuhisa (2013)
  • Publisher: Multidisciplinary Digital Publishing Institute
  • Journal: Antibodies (issn: 2073-4468)
  • Related identifiers: doi: 10.3390/antib2010093
  • Subject: single-chain Fv (scFv) | recombinant antibody technology | RC581-607 | hapten | Immunologic diseases. Allergy | narcotic | morphine

An immune phage library derived from mice, hyperimmunized with morphine-conjugated BSA, was used to isolate a single-chain Fv (scFv) clone, M86, with binding activity to morphine-conjugated thyroglobulin (morphine-C-Tg) but not to codeine-, cocaine-, or ketamine-conjuga... View more
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    1q0y Protein Data Bank
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