Characterization of a Single Chain Fv Antibody that Reacts with Free Morphine

Article, Other literature type English OPEN
Kazuhisa Sugimura; Yuta Hamazoe; Koji Arizono; Shinya Kohra; Koichi Tanaka; Mariko Kamegawa; Miho Matsukizono;

An immune phage library derived from mice, hyperimmunized with morphine-conjugated BSA, was used to isolate a single-chain Fv (scFv) clone, M86, with binding activity to morphine-conjugated thyroglobulin (morphine-C-Tg) but not to codeine-, cocaine-, or ketamine-conjuga... View more
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