clockwork orange Encodes a Transcriptional Repressor Important for Circadian-Clock Amplitude in Drosophila

Article, Other literature type English OPEN
Lim, Chunghun ; Chung, Brian Y. ; Pitman, Jena L. ; McGill, Jermaine J. ; Pradhan, Suraj ; Lee, Jongbin ; Keegan, Kevin P. ; Choe, Joonho ; Allada, Ravi (2007)
  • Publisher: Elsevier BV
  • Journal: Current Biology, volume 17, issue 12, pages 1,082-1,089 (issn: 0960-9822)
  • Related identifiers: pmc: PMC1963421, doi: 10.1016/j.cub.2007.05.039
  • Subject: Agricultural and Biological Sciences(all) | Biochemistry, Genetics and Molecular Biology(all) | Article

Gene transcription is a central timekeeping process in animal clocks. In Drosophila, the basic helix-loop helix (bHLH)-PAS transcription factor heterodimer, CLOCK (CLK)/CYCLE(CYC) transcriptionally activates the clock components period (per), timeless (tim), Par domain ... View more
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