Error-prone polymerase activity causes multinucleotide mutations in humans

Other literature type, Preprint English OPEN
Harris, Kelley; Nielsen, Rasmus;
(2014)

About 2% of human genetic polymorphisms have been hypothesized to arise via multinucleotide mutations (MNMs), complex events that generate SNPs at multiple sites in a single generation. MNMs have the potential to accelerate the pace at which single genes evolve and to c... View more
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