Malaria's Missing Number: Calculating the Human Component of R0 by a Within-Host Mechanistic Model of Plasmodium falciparum Infection and Transmission

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Geoffrey L Johnston; David L Smith; David A Fidock;
  • Publisher: Public Library of Science
  • Journal: PLoS Computational Biology, volume 9, issue 4 (issn: 1553-734X, eissn: 1553-7358)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1371/journal.pcbi.1003025, pmc: PMC3630126
  • Subject: Applied Mathematics | Research Article | Biology | Tropical Diseases (Non-Neglected) | Mathematics | Infectious Diseases | Infectious Disease Epidemiology | Medicine | Malaria | QH301-705.5 | Epidemiology | Population Biology | Biology (General) | Plasmodium Malariae
    mesheuropmc: parasitic diseases

Human infection by malarial parasites of the genus Plasmodium begins with the bite of an infected Anopheles mosquito. Current estimates place malaria mortality at over 650,000 individuals each year, mostly in African children. Efforts to reduce disease burden can benefi... View more
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