Reduction of lung metastasis, cell invasion, and adhesion in mouse melanoma by statin-induced blockade of the Rho/Rho-associated coiled-coil-containing protein kinase pathway
- Publisher: BioMed Central
Journal of Experimental & Clinical Cancer Research : CR,
(issn: 0392-9078, eissn: 1756-9966)
RC254-282 | Research | Neoplasms. Tumors. Oncology. Including cancer and carcinogens
<p>Abstract</p> <p>Background</p> <p>Melanomas are highly malignant and have high metastatic potential; hence, there is a need for new therapeutic strategies to prevent cell metastasis. In the present study, we investigated whether statins inhibit tumor cell migration, ...