Social defeat stress induces depression-like behavior and alters spine morphology in the hippocampus of adolescent male C57BL/6 mice

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Iñiguez, Sergio D.; Aubry, Antonio; Riggs, Lace M.; Alipio, Jason B.; Zanca, Roseanna M.; Flores-Ramirez, Francisco J.; Hernandez, Mirella A.; Nieto, Steven J.; Musheyev, David; Serrano, Peter A.;
  • Publisher: Elsevier
  • Journal: Neurobiology of Stress,volume 5,pages54-64 (issn: 2352-2895, eissn: 2352-2895)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC5154707, doi: 10.1016/j.ynstr.2016.07.001
  • Subject: Tail suspension test | Neurology. Diseases of the nervous system | Neurosciences. Biological psychiatry. Neuropsychiatry | RC321-571 | RC346-429 | CA1 | Original Research Article | Neurophysiology and neuropsychology | Juvenile | Depression | QP351-495 | Dopamine | Bullying | GluA2

Social stress, including bullying during adolescence, is a risk factor for common psychopathologies such as depression. To investigate the neural mechanisms associated with juvenile social stress-induced mood-related endophenotypes, we examined the behavioral, morpholog... View more