Abnormal Osmotic Avoidance Behavior in C. elegans Is Associated with Increased Hypertonic Stress Resistance and Improved Proteostasis.

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Lee, Elaine C.; Kim, Heejung; Ditano, Jennifer; Manion, Dacie; King, Benjamin L.; Strange, Kevin;
(2016)
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 11,issue 4 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC4844114, doi: 10.1371/journal.pone.0154156
  • Subject: Caenorhabditis | Animal Models | Research Article | Classical Mechanics | Neurons | Polymer chemistry | Epigenetics | Physical Sciences | Genetics | Proteins | Physics | Animals | Osmotic Pressure | Chemistry | Cellular Types | Biology and Life Sciences | RNA | Tonicity | Neuroscience | Hypertonic | Research and Analysis Methods | Nematoda | Damage Mechanics | Genetic interference | Animal Cells | Caenorhabditis Elegans | Medicine | Pressure | Nucleic acids | Monomers (Chemistry) | Glycerol | Cellular Neuroscience | Q | R | Cell Biology | Model Organisms | Protein Aggregation | Biochemistry | Science | Organisms | Invertebrates | RNA interference | Gene Expression
    mesheuropmc: fungi

Protein function is controlled by the cellular proteostasis network. Proteostasis is energetically costly and those costs must be balanced with the energy needs of other physiological functions. Hypertonic stress causes widespread protein damage in C. elegans. Suppressi... View more
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