Characterization of Regulatory Dendritic Cells That Mitigate Acute Graft-versus-Host Disease in Older Mice Following Allogeneic Bone Marrow Transplantation

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Scroggins, Sabrina M.; Olivier, Alicia K.; Meyerholz, David K.; Schlueter, Annette J.;
  • Publisher: Public Library of Science
  • Journal: PLoS ONE,volume 8,issue 9 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: doi: 10.1371/journal.pone.0075158, pmc: PMC3769303
  • Subject: Q | R | Research Article | Science | Medicine
    mesheuropmc: surgical procedures, operative | chemical and pharmacologic phenomena | immune system diseases

Despite improvements in human leukocyte antigen matching and pharmacologic prophylaxis, acute graft-versus-host disease (GVHD) is often a fatal complication following hematopoietic stem cell transplant (HSCT). Older HSCT recipients experience significantly increased mor... View more
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