Experimental model of traumatic ulcer in the cheek mucosa of rats

Article Portuguese OPEN
Cavalcante, Galyléia Meneses ; de Paula, Renata Janaína Sousa ; de Souza, Leonardo Peres [UNESP] ; Sousa, Fabrício Bitu ; Mota, Mário Rogério Lima ; Alves, Ana Paula Negreiros Nunes (2011)
  • Publisher: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
  • Journal: (issn: 0102-8650, eissn: 1678-2674)
  • Related identifiers: doi: 10.1590/S0102-86502011000300012
  • Subject: Oral Ulcer | reliability | Mucosa Bucal | Wound heling | abrasion | mouth ulcer | scoring system | body weight | weight reduction | Time Factors | analysis of variance | histology | Mouth Mucosa | scalpel | Rats | Animals | animal model | Wound Healing | cost | rat | cheek mucosa | disease course | Cheek | reproducibility | animal experiment | Cicatrização de Feridas | Disease Models, Animal | Úlcera | RD1-811 | animal tissue | Ulcer | nonhuman | Ratos | Male | Surgery

PURPOSE: To establish an experimental model of traumatic ulcer in rat cheek mucosa for utilization in future alternative therapy studies. METHODS: A total of 60 adult male rats (250 - 300g) were used. Ulceration of the left cheek mucosa was provoked by abrasion using a ... View more