Comparison of Inhibitory Effect of Curcumin Nanoparticles and Free Curcumin in Human Telomerase Reverse Transcriptase Gene Expression in Breast Cancer

Article, Other literature type English OPEN
Nosratollah Zarghami ; Abbas Rami ; Fatemeh Kazemi-Lomedasht (2013)
  • Publisher: Tabriz University of Medical Sciences
  • Journal: Advanced Pharmaceutical Bulletin (issn: 2228-5881, eissn: 2251-7308)
  • Related identifiers: doi: 10.5681/apb.2013.021, pmc: PMC3846029
  • Subject: Research Article | Telomerase | RM1-950 | Therapeutics. Pharmacology | Breast cancer | Drug delivery | Anti cancer drug | Target therapy
    mesheuropmc: polycyclic compounds

Purpose: Telomerase is expressed in most cancers, including breast cancer. Curcumin, a polyphenolic compound that obtained from the herb of Curcuma longa, has many anticancer effects. But, its effect is low due to poor water solubility. In order to improve its solubilit... View more
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