Replication of 6 obesity genes in a meta-analysis of genome-wide association studies from diverse ancestries.

Article English OPEN
Li-Jun Tan ; Hu Zhu ; Hao He ; Ke-Hao Wu ; Jian Li ; Xiang-Ding Chen ; Ji-Gang Zhang ; Hui Shen ; Qing Tian ; Marie Krousel-Wood ; Christopher J Papasian ; Claude Bouchard ; Louis Pérusse ; Hong-Wen Deng
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE, volume 9, issue 5 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: pmc: PMC4039436, doi: 10.1371/journal.pone.0096149
  • Subject: Human Genetics | Research Article | Cultural Anthropology | Body Weight | Population Groupings | Epidemiology | Genetics | People and Places | Obesity | Anthropology | Biology and Life Sciences | Physiology | Medicine | Genetic Epidemiology | Biomarker Epidemiology | Ethnicities | Q | R | Physiological Parameters | Social Sciences | Science | Genetic Association Studies | Medicine and Health Sciences | Ethnic Differences
    mesheuropmc: nutritional and metabolic diseases

Obesity is a major public health problem with a significant genetic component. Multiple DNA polymorphisms/genes have been shown to be strongly associated with obesity, typically in populations of European descent. The aim of this study was to verify the extent to which ... View more