A Comprehensive Behavioral Test Battery to Assess Learning and Memory in 129S6/Tg2576 Mice.

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Andrea Wolf; Björn Bauer; Erin L Abner; Tal Ashkenazy-Frolinger; Anika M S Hartz;
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 11,issue 1 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: pmc: PMC4726499, doi: 10.1371/journal.pone.0147733
  • Subject: Mouse Models | Object Recognition | Animal Models | Biotechnology | Research Article | Memory | Cognitive Psychology | Learning | Mice | Rodents | Perception | Agriculture | Psychology | Animals | Behavior | Neurology | Genetically Modified Animals | Biology and Life Sciences | Cognition | Neuroscience | Animal Behavior | Research and Analysis Methods | Medicine | Genetic Engineering | Vertebrates | Q | Agricultural Biotechnology | R | Model Organisms | Mammals | Learning and Memory | Cognitive Neurology | Social Sciences | Science | Organisms | Cognitive Impairment | Genetically Modified Organisms | Medicine and Health Sciences | Cognitive Neuroscience | Zoology | Cognitive Science
    mesheuropmc: mental disorders

Transgenic Tg2576 mice overexpressing human amyloid precursor protein (hAPP) are a widely used Alzheimer's disease (AD) mouse model to evaluate treatment effects on amyloid beta (Aβ) pathology and cognition. Tg2576 mice on a B6;SJL background strain carry a recessive rd... View more
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