Adaptation to Lactose in Lactase Non Persistent People: Effects on Intolerance and the Relationship between Dairy Food Consumption and Evalution of Diseases

Other literature type, Article English OPEN
Szilagyi, Andrew;
(2015)

Dairy foods contain complex nutrients which interact with the host. Yet, evolution of lactase persistence has divided the human species into those that can or cannot digest lactose in adulthood. Such a ubiquitous trait has differential effects on humanity. The literatur... View more
  • References (158)
    158 references, page 1 of 16

    1. Swallow, D.M. Genetics of lactase persistence and lactose intolerance. Ann. Hum. Genet. 2003, 37, 197-219. [CrossRef] [PubMed]

    2. Tishkoff, S.A.; Reed, F.A.; Ranciaro, A.; Voight, B.F.; Babbitt, C.C.; Silverman, J.S. Convergent adaptation of human lactase persistence in Africa and Europe. Nat. Genet. 2007, 39, 31-40. [CrossRef] [PubMed]

    3. Prentice, A.M. Dairy products in global public health. Am. J. Clin. Nutr. 2014, 99, 1212S-1216S. [CrossRef] [PubMed]

    4. Holden, C.; Mace, R. Phylogenetic analysis of the evolution of lactose digestion in adults. Hum. Biol. 1997, 69, 605-628. [CrossRef] [PubMed]

    5. Flatz, G.; Rotthauwe, H.W. Lactose nutrition and natural selection. Lancet 1973, 2, 76-77. [CrossRef]

    6. Bersaglieri, T.; Sabeti, P.C.; Patterson, N.; Vanderploeg, T.; Schaffner, S.F.; Drake, J.A. Genetic signatures of strong recent positive selection at the lactase gene. Am. J. Hum. Genet. 2004, 74, 1111-1120. [CrossRef] [PubMed]

    7. Gerbault, P.; Liebert, A.; Swallow, D.M.; Thomas, M.G. Lactose malabsorption and nutrition. In Advanced Nutrition and Dietetics in Gastroenterology, 1st ed.; Lomer, M., Ed.; John Wiley and Sons Ltd: Oxford, UK, 2014; pp. 202-209.

    8. Shrier, I.; Szilagyi, A.; Correa, J.A. Impact of lactose containing foods and the genetics of lactase on diseases: An analytical review of population data. Cancer Nutr. 2008, 60, 292-300. [CrossRef] [PubMed]

    9. Scrimshaw, N.S.; Murray, E.B. Prevalence of lactose maldigestion. Am. J. Clin. Nutr. 1988, 48, 1086-1098.

    10. Hertzler, S.R.; Savaiano, D.A. Colonic adaptation to daily lactose feeding in lactose maldigesters reduces lactose intolerance. Am. J. Clin. Nutr. 1996, 64, 232-236. [PubMed]

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