Impact of infusion speed on the safety and effectiveness of prothrombin complex concentrate

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Pabinger , Ingrid; Tiede , Andreas; Kalina , Uwe; Knaub , Sigurd; Germann , Reinhard; Ostermann , Helmut;
  • Publisher: Springer Verlag
  • Identifiers: doi: 10.1007/s00277-009-0830-7
  • Subject: Infusion speed | Coumarins | Anticoagulation reversal | Prothrombin complex concentrates | Surgery | Hemorrhage

International audience; Prothrombin complex concentrate (PCC) infusion is preferred for emergency reversal of coumarin therapy. Rapid infusion can potentially save crucial time; however, the possible impact of high infusion speed on PCC safety and effectiveness has not ... View more
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