Antiepileptic Effect of Uncaria rhynchophylla and Rhynchophylline Involved in the Initiation of c-Jun N-Terminal Kinase Phosphorylation of MAPK Signal Pathways in Acute Seizures of Kainic Acid-Treated Rats

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Hsu, Hsin-Cheng; Tang, Nou-Ying; Liu, Chung-Hsiang; Hsieh, Ching-Liang;
  • Publisher: Hindawi Publishing Corporation
  • Journal: Evidence-based Complementary and Alternative Medicine : eCAM,volume 2,013 (issn: 1741-427X, eissn: 1741-4288)
  • Related identifiers: doi: 10.1155/2013/961289, pmc: PMC3867957
  • Subject: Other systems of medicine | Research Article | RZ201-999 | Article Subject

Seizures cause inflammation of the central nervous system. The extent of the inflammation is related to the severity and recurrence of the seizures. Cell surface receptors are stimulated by stimulators such as kainic acid (KA), which causes intracellular mitogen-activat... View more
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