Authentication of Primordial Characteristics of the CLBL-1 Cell Line Prove the Integrity of a Canine B-Cell Lymphoma in a Murine In Vivo Model

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Barbara C Rütgen; Saskia Willenbrock; Nicola Reimann-Berg; Ingrid Walter; Andrea Fuchs-Baumgartinger; Siegfried Wagner; Boris Kovacic; Sabine E Essler; Ilse Schwendenwein; Ingo Nolte; Armin Saalmüller; Hugo Murua Escobar;
  • Publisher: Public Library of Science
  • Journal: PLoS ONE,volume 7,issue 6 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC3386195, doi: 10.1371/journal.pone.0040078
  • Subject: Animal Models | Research Article | Cytogenetics | Small Animals | Oncology | Mouse | Genetics | Cancer Genetics | Animal Types | Laboratory Animals | Immunology | Biology | Cytogenetic Analysis | Veterinary Science | Immune Cells | Medicine | Basic Cancer Research | Tumor Physiology | Q | R | B Cells | Model Organisms | Science | Veterinary Medicine | Veterinary Oncology
    mesheuropmc: hemic and lymphatic diseases

Cell lines are key tools in cancer research allowing the generation of neoplasias in animal models resembling the initial tumours able to mimic the original neoplasias closely in vivo. Canine lymphoma is the major hematopoietic malignancy in dogs and considered as a val... View more
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