Reproducibility of NMR Analysis of Urine Samples: Impact of Sample Preparation, Storage Conditions, and Animal Health Status

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Schreier, Christina ; Kremer, Werner ; Huber, Fritz ; Neumann, Sindy ; Pagel, Philipp ; Lienemann, Kai ; Pestel, Sabine (2013)
  • Publisher: Hindawi Publishing Corporation
  • Journal: BioMed Research International, volume 2,013 (issn: 2314-6133, eissn: 2314-6141)
  • Related identifiers: pmc: PMC3705931, doi: 10.1155/2013/878374
  • Subject: R | Research Article | Medicine | Article Subject

Introduction. Spectroscopic analysis of urine samples from laboratory animals can be used to predict the efficacy and side effects of drugs. This employs methods combining 1H NMR spectroscopy with quantification of biomarkers or with multivariate data analysis. The most... View more
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