Protein kinase C signaling and cell cycle regulation

Article English OPEN
Black, Adrian R.; Black, Jennifer D.;
  • Publisher: Frontiers Media S.A.
  • Journal: Frontiers in Immunology,volume 3 (issn: 1664-3224, eissn: 1664-3224)
  • Related identifiers: pmc: PMC3547298, doi: 10.3389/fimmu.2012.00423/full, doi: 10.3389/fimmu.2012.00423
  • Subject: T cell activation | Review Article | RC581-607 | cyclin | signal transduction | cell cycle | PKC | cyclin-dependent kinase | Immunologic diseases. Allergy | Immunology | cyclin-dependent kinase inhibitor | protein kinase C

A link between T cell proliferation and the protein kinase C (PKC) family of serine/threonine kinases has been recognized for about thirty years. However, despite the wealth of information on PKC-mediated control of T cell activation, understanding of the effects of PK... View more
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