Mesenchymal Stem Cell-Derived Microvesicles Support Ex Vivo Expansion of Cord Blood-Derived CD34+ Cells

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Xie, Hui; Sun, Li; Zhang, Liming; Liu, Teng; Chen, Li; Zhao, Aiqi; Lei, Qian; Gao, Fei; Zou, Ping; Li, Qiubai; Guo, An-yuan; Chen, Zhichao; Wang, Hongxiang; (2016)
  • Publisher: Hindawi Publishing Corporation
  • Journal: Stem Cells International,volume 2,016 (issn: 1687-966X, eissn: 1687-9678)
  • Related identifiers: pmc: PMC4799819, doi: 10.1155/2016/6493241
  • Subject: Research Article | Internal medicine | RC31-1245 | Article Subject

Mesenchymal stem cells (MSCs) are known to support the characteristic properties of hematopoietic stem and progenitor cells (HSPCs) in the bone marrow hematopoietic microenvironment. MSCs are used in coculture systems as a feeder layer for the ex vivo expansion of umbil... View more
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