Analysis of T cell responses to chimpanzee adenovirus vectors encoding HIV gag–pol–nef antigen
Le Heron, A.
- Publisher: Elsevier Science
(issn: 0264-410X, eissn: 1873-2518)
Immunology and Microbiology(all) | 06 Biological Sciences | Infectious Diseases | IMMUNITY | Medicine, Research & Experimental | Mouse | HIV | LOAD | TEST-OF-CONCEPT | Adenovirus | PROTEIN | 07 Agricultural And Veterinary Sciences | Molecular Medicine | Research & Experimental Medicine | Immunology | Public Health, Environmental and Occupational Health | DELIVERY | EXPRESSION | Life Sciences & Biomedicine | Immunogenicity | EFFICACY | Article | Vaccine | Vectors | Science & Technology | veterinary(all) | Virology | 11 Medical And Health Sciences | CHALLENGE
mesheuropmc: viruses | virus diseases
Adenoviruses have been shown to be both immunogenic and efficient at presenting HIV proteins but recent trials have suggested that they may play a role in increasing the risk of HIV acquisition. This risk may be associated with the presence of pre-existing immunity to t...