The Caenorhabditis elegans Mucin-Like Protein OSM-8 Negatively Regulates Osmosensitive Physiology Via the Transmembrane Protein PTR-23

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Anne-Katrin Rohlfing; Yana Miteva; Lorenza Moronetti; Liping He; Todd Lamitina;
  • Publisher: Public Library of Science
  • Journal: PLoS Genetics,volume 7,issue 1 (issn: 1553-7390, eissn: 1553-7404)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1371/journal.pgen.1001267, pmc: PMC3017116
  • Subject: QH426-470 | Genetics | Research Article | Genetics and Genomics/Functional Genomics | Genetics and Genomics/Gene Function | Physiology/Integrative Physiology | Physiology/Renal, Fluid, and Electrolyte Physiology | Physiology/Genomics | Physiology/Cell Signaling
    mesheuropmc: fungi

The molecular mechanisms of animal cell osmoregulation are poorly understood. Genetic studies of osmoregulation in yeast have identified mucin-like proteins as critical regulators of osmosensitive signaling and gene expression. Whether mucins play similar roles in highe... View more
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