MicroRNA-184 is a downstream effector of albuminuria driving renal fibrosis in rats with diabetic nephropathy

Article English OPEN
Zanchi, Cristina ; Macconi, Daniela ; Trionfini, Piera ; Tomasoni, Susanna ; Rottoli, Daniela ; Locatelli, Monica ; Rudnicki, Michael ; Vandesompele, Jo ; Mestdagh, Pieter ; Remuzzi, Giuseppe ; Benigni, Ariela ; Zoja, Carlamaria (2017)
  • Publisher: Springer Nature
  • Journal: Diabetologia, volume 60, issue 6, pages 1,114-1,125 (issn: 0012-186X, eissn: 1432-0428)
  • Related identifiers: pmc: PMC5423990, doi: 10.1007/s00125-017-4248-9, doi: 10.13039/501100004963
  • Subject: Biology and Life Sciences | EXPRESSION | DIFFERENTIATION | GENE | Internal Medicine | Article | ACID | DEMETHYLATION | Albuminuria | PATHOGENESIS | Zucker diabetic fatty rats | CELLS | Endocrinology, Diabetes and Metabolism | PROTEIN | MIR-184 | Fibrosis | MECHANISMS | Diabetic nephropathy

Aims/hypothesis Renal fibrosis is a common complication of diabetic nephropathy and is a major cause of end-stage renal disease. Despite the suggested link between renal fibrosis and microRNA (miRNA) dysregulation in diabetic nephropathy, the identification of the speci... View more
Share - Bookmark