Augmented TLR2 expression on monocytes in both human Kawasaki disease and a mouse model of coronary arteritis.

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Lin, I-Chun; Kuo, Ho-Chang; Lin, Ying-Jui; Wang, Feng-Shen; Wang, Lin; Huang, Shun-Chen; Chien, Shao-Ju; Huang, Chien-Fu; Wang, Chih-Lu; Yu, Hong-Ren; Chen, Rong-Fu; Yang, Kuender D.;
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 7,issue 6 (issn: 1932-6203, eissn: 1932-6203)
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  • Related identifiers: pmc: PMC3380902, doi: 10.1371/journal.pone.0038635
  • Subject: Autoimmune Diseases | Animal Models | Research Article | Biology | Antigen-Presenting Cells | Molecular Cell Biology | Signal Transduction | Immune Cells | Immunologic Receptor Signaling | Medicine | Membrane Receptor Signaling | Mouse | Q | R | Immunopathology | Model Organisms | Immune Response | Clinical Immunology | Pediatrics | Science | Pediatric Cardiology | Immunology | Kawasaki Disease

BACKGROUND: Kawasaki disease (KD) of unknown immunopathogenesis is an acute febrile systemic vasculitis and the leading cause of acquired heart diseases in childhood. To search for a better strategy for the prevention and treatment of KD, this study compared and validat... View more
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