VacA and CagA Status as Biomarker of Two Opposite End Outcomes of Helicobacter pylori Infection (Gastric Cancer and Duodenal Ulcer) in a Moroccan Population.

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El Khadir, Mounia; Alaoui Boukhris, Samia; Benajah, Dafr-Allah; El Rhazi, Karima; Ibrahimi, Sidi Adil; El Abkari, Mohamed; Harmouch, Taoufiq; Nejjari, Chakib; Mahmoud, Mustapha; Benlemlih, Mohamed; Bennani, Bahia;
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 12,issue 1 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1371/journal.pone.0170616, pmc: PMC5268467
  • Subject: Helicobacter Pylori | Molecular Biology | Microbial Pathogens | Research Article | Variant Genotypes | Pathology and Laboratory Medicine | Oncology | Artificial Gene Amplification and Extension | Genetics | Pathogens | Molecular Biology Techniques | Helicobacter | Cancers and Neoplasms | Gastritis | Polymerase Chain Reaction | Biology and Life Sciences | Surgical and Invasive Medical Procedures | Gastric Cancer | Gastroenterology and Hepatology | Research and Analysis Methods | Microbiology | Medicine | Bacterial Pathogens | Heredity | Virulence Factors | Gastrointestinal Infections | Medical Microbiology | Q | R | Genetic Mapping | Gastrointestinal Tumors | Science | Organisms | Biopsy | Medicine and Health Sciences
    mesheuropmc: bacteria | bacterial infections and mycoses | digestive system diseases

Helicobacter pylori (H. pylori) infection induces inflammation of the gastric mucosa, which may progress to precancerous lesions leading to gastric cancer. Pathological determinism is associated to some virulence genes of the bacterium, notably the vacA and cagA genes. ... View more
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