Common Genetic Variants Found in HLA and KIR Immune Genes in Autism Spectrum Disorder

Article, Other literature type OPEN
Torres, Anthony R. ; Sweeten, Thayne ; Johnson, Randall C. ; Odell, Dennis ; Westover, Jonna B. ; Bray-Ward, Patricia ; Ward, David C. ; Davies, Christopher J. ; Thomas, Aaron J. ; Croen, Lisa A. ; Benson, Michael (2016)
  • Publisher: Hosted by Utah State University Libraries
  • Journal: Frontiers in Neuroscience, volume 10 (issn: 1662-453X, eissn: 1662-453X)
  • Related identifiers: pmc: PMC5071356, doi: 10.3389/fnins.2016.00463, doi: 10.3389/fnins.2016.00463/full
  • Subject: haplotype | common genetic variant | Neurosciences. Biological psychiatry. Neuropsychiatry | KIR | Neuroscience and Neurobiology | Neuroscience | Review | RC321-571 | HLA | autism

The common variant - common disease hypothesis was proposed to explain diseases with strong inheritance. This model suggests that a genetic disease is the result of the combination of several common genetic variants. Common genetic variants are described as a 5% frequ... View more
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