Common Genetic Variants Found in HLA and KIR Immune Genes in Autism Spectrum Disorder

Article, Other literature type English OPEN
Torres, Anthony R.; Sweeten, Thayne L.; Johnson, Randall C.; Odell, Dennis; Westover, Jonna B.; Bray-Ward, Patricia; Ward, David C.; Davies, Christopher J.; Thomas, Aaron J.; Croen, Lisa A.; Benson, Michael;
  • Publisher: Frontiers Media S.A.
  • Journal: Frontiers in Neuroscience,volume 10 (issn: 1662-453X, eissn: 1662-453X)
  • Related identifiers: pmc: PMC5071356, doi: 10.3389/fnins.2016.00463, doi: 10.3389/fnins.2016.00463/full
  • Subject: haplotype | common genetic variant | Neurosciences. Biological psychiatry. Neuropsychiatry | KIR | Neuroscience and Neurobiology | Neuroscience | Review | RC321-571 | HLA | autism

The common variant - common disease hypothesis was proposed to explain diseases with strong inheritance. This model suggests that a genetic disease is the result of the combination of several common genetic variants. Common genetic variants are described as a 5% frequ... View more
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