Positive Modulation Effect of 8-Week Consumption of Kaempferia parviflora on Health-Related Physical Fitness and Oxidative Status in Healthy Elderly Volunteers

Article English OPEN
Jintanaporn Wattanathorn ; Supaporn Muchimapura ; Terdthai Tong-Un ; Narisara Saenghong ; Wipawee Thukhum-Mee ; Bungorn Sripanidkulchai (2012)
  • Publisher: Hindawi Limited
  • Journal: Evidence-Based Complementary and Alternative Medicine, volume 2,012 (issn: 1741-427X, eissn: 1741-4288)
  • Related identifiers: pmc: PMC3415259, doi: 10.1155/2012/732816
  • Subject: Other systems of medicine | Research Article | RZ201-999 | Article Subject

Health-related physical fitness declines as the age advances. Oxidative stress is reported to contribute the crucial role on this phenomenon. This condition is also enhanced by antioxidant. Therefore, we aimed to determine the effect of Kaempferia parviflora, a plant reputed for antifatigue, longevity promotion, and antioxidant effects, on health-related quality physical fitness and oxidative status of the healthy elderly volunteers. Total 45 subjects had been randomized to receive placebo or K. parviflora extract at doses of 25 or 90 mg once daily for 8 weeks. They were determined baseline data of physical performance using 30 sec chair stand test, hand grip test, 6 min walk test, and tandem test. Serum oxidative stress markers including malondialdehde (MDA) level and the activities of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) were also assayed. All assessments were performed every 4 weeks throughout the 8-week study period. The results showed that K. parviflora increased performance in 30-second chair stand test and 6 min walk test together with the increased all scavenger enzymes activities and the decreased MDA level. Therefore, K. parviflora can enhance physical fitness partly via the decreased oxidative stress. In conclusion, K. parviflora is the potential health supplement for elderly. However, further study is required.
  • References (27)
    27 references, page 1 of 3

    Haskell, W. L., Kiernan, M.. Methodologic issues in measuring physical activity and physical fitness when evaluating the role of dietary supplements for physically active people. American Journal of Clinical Nutrition. 2000; 72: S541-S550

    De la Fuente, M.. Effects of antioxidants on immune system ageing. European Journal of Clinical Nutrition. 2002; 56 (3): S5-S8

    Aust, S. D., Morehouse, L. A., Thomas, C. E.. Role of metals in oxygen radical reactions. Journal of Free Radicals in Biology and Medicine. 1985; 1 (1): 3-25

    Sevanian, A., Hochstein, P.. Mechanisms and consequences of lipid peroxidation in biological systems. Annual Review of Nutrition. 1985; 5: 365-390

    Pansarasa, O., Castagna, L., Colombi, B., Vecchiet, J., Felzani, G., Marzatico, F.. Age and sex differences in human skeletal muscle: role of reactive oxygen species. Free Radical Research. 2000; 33 (3): 287-293

    Fanò, G., Mecocci, P., Vecchiet, J., Belia, S., Fulle, S., Polidori, M. C., Felzani, G., Senin, U., Vecchiet, L., Beal, M. F.. Age and sex influence on oxidative damage and functional status in human skeletal muscle. Journal of Muscle Research and Cell Motility. 2001; 22 (4): 345-351

    Cesari, M., Pahor, M., Bartali, B., Cherubini, A., Penninx, B. W., Williams, G. R., Atkinson, H., Martin, A., Guralnik, J. M., Ferrucci, L.. Antioxidants and physical performance in elderly persons: the Invecchiare in Chianti (InCHIANTI) study. American Journal of Clinical Nutrition. 2004; 79 (2): 289-294

    Chesney, C. M., Elam, M. B., Herd, J. A., Davis, K. B., Garg, R., Hunninghake, D., Kennedy, J. W., Applegate, W. B.. Effect of niacin, warfarin, and antioxidant therapy on coagulation parameters in patients with peripheral arterial disease in the Arterial Disease Multiple Intervention Trial (ADMIT). American Heart Journal. 2000; 140 (4): 631-636

    Joshi, S. G.. Medicinal Plants. 2000

    Sutthanut, K., Sripanidkulchai, B., Yenjai, C., Jay, M.. Simultaneous identification and quantitation of 11 flavonoid constituents in Kaempferia parviflora by gas chromatography. Journal of Chromatography A. 2007; 1143 (1-2): 227-233

  • Metrics
    views in OpenAIRE
    views in local repository
    downloads in local repository
Share - Bookmark