Neuroprotection from NMDA excitotoxic lesion by Cu/Zn superoxide dismutase gene delivery to the postnatal rat brain by a modular protein vector

Article English OPEN
Castellano Bernardo; Villaverde Antoni; González Pau; Arís Anna; Acarin Laia; Peluffo Hugo; González Berta; (2006)
  • Publisher: BMC
  • Journal: BMC Neuroscience,volume 7,pages35-35 (issn: 1471-2202, eissn: 1471-2202)
  • Related identifiers: pmc: PMC1462999, doi: 10.1186/1471-2202-7-35
  • Subject: Research Article | Neurosciences. Biological psychiatry. Neuropsychiatry | RC321-571 | Neurophysiology and neuropsychology | QP351-495

<p>Abstract</p> <p>Background</p> <p>Superoxide mediated oxidative stress is a key neuropathologic mechanism in acute central nervous system injuries. We have analyzed the neuroprotective efficacy of the transient overexpression of antioxidant enzyme Cu/Zn Superoxide di... View more
Share - Bookmark