Implication de l’interférence entre réplication et transcription au cours du développement du cancer

Doctoral thesis French OPEN
Promonet , Alexy;
  • Publisher: HAL CCSD
  • Subject: Checkpoint | L'instabilité du génome | Réplication | R-Loop | Cancer | DNA replication | Genomic instability | [ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathology | Point de contrôle

Genome instability is a hallmark of cancer cells. It has been proposed that at early stages of the cancer process, genomic instability is caused by oncogene-induced replication stress, a poorly-understood process characterized with the accumulation of stalled replicatio... View more
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