3,5,4′-trihydroxy-6,7,3′-trimethoxyflavone protects against beta amyloid-induced neurotoxicity through antioxidative activity and interference with cell signaling

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Telerman, Alona; Ofir, Rivka; Kashman, Yoel; Elmann, Anat;
  • Publisher: BioMed Central
  • Journal: BMC Complementary and Alternative Medicine,volume 17 (issn: 1472-6882, eissn: 1472-6882)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC5481959, doi: 10.1186/s12906-017-1840-y
  • Subject: Alzheimer’s disease | Other systems of medicine | 3,5,4′-trihydroxy-6,7,3′-trimethoxyflavone | Research Article | Mitogen-activated protein kinases | RZ201-999 | Flavonoids | Neurons | Amyloid beta | Achillea fragrantissima

Abstract Background Alzheimer’s disease is a neurodegenerative disease, characterized by progressive decline in memory and cognitive functions, that results from loss of neurons in the brain. Amyloid beta (Aβ) protein and oxidative stress are major contributors to Alzhe... View more
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