Scaling of brain metabolism with a fixed energy budget per neuron: implications for neuronal activity, plasticity and evolution.

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Herculano-Houzel, Suzana;
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 6,issue 3 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC3046985, doi: 10.1371/journal.pone.0017514
  • Subject: Research Article | Biology | Organismal Evolution | Neuroscience | Medicine | Animal Evolution | Q | R | Evolutionary Biology | Bioenergetics | Human Evolution | Biochemistry | Science | Neural Homeostasis | Metabolism
    mesheuropmc: nervous system

It is usually considered that larger brains have larger neurons, which consume more energy individually, and are therefore accompanied by a larger number of glial cells per neuron. These notions, however, have never been tested. Based on glucose and oxygen metabolic rat... View more
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