Variation in alternative splicing across human tissues

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Yeo, Gene; Holste, Dirk; Kreiman, Gabriel; Burge, Christopher B;

Background: Alternative pre-mRNA splicing (AS) is widely used by higher eukaryotes to generate different protein isoforms in specific cell or tissue types. To compare AS events across human tissues, we analyzed the splicing patterns of genomically aligned expressed sequ... View more
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