Adipsin Is Associated with Multiple Sclerosis: A Follow-Up Study of Adipokines

Article English OPEN
Natarajan, Renuka; Hagman, Sanna; Hämälainen, Mari; Leppänen, Tiina; Dastidar, Prasun; Moilanen, Eeva; Elovaara, Irina;
(2015)

Background and Objective. The role of adipokines in regulation of immune responses has been recognized, but very little is known about their impact on multiple sclerosis (MS). In this study, we analysed whether the major adipokines are differentially expressed in plasma... View more
  • References (41)
    41 references, page 1 of 5

    Friese, M. A., Schattling, B., Fugger, L.. Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis. Nature Reviews Neurology. 2014; 10 (4): 225-238

    Ellwardt, E., Zipp, F.. Molecular mechanisms linking neuroinflammation and neurodegeneration in MS. Experimental Neurology. 2014; 262: 8-17

    Munger, K. L., Chitnis, T., Ascherio, A.. Body size and risk of MS in two cohorts of US women. Neurology. 2009; 73 (19): 1543-1550

    Hedström, A. K., Olsson, T., Alfredsson, L.. High body mass index before age 20 is associated with increased risk for multiple sclerosis in both men and women. Multiple Sclerosis. 2012; 18 (9): 1334-1336

    Versini, M., Jeandel, P.-Y., Rosenthal, E., Shoenfeld, Y.. Obesity in autoimmune diseases: not a passive bystander. Autoimmunity Reviews. 2014; 13 (9): 981-1000

    Exley, M. A., Hand, L., O'Shea, D., Lynch, L.. Interplay between the immune system and adipose tissue in obesity. Journal of Endocrinology. 2014; 223 (2): R41-R48

    Aguilar-Valles, A., Inoue, W., Rummel, C., Luheshi, G. N.. Obesity, adipokines and neuroinflammation. Neuropharmacology. 2015; 96: 124-134

    Rotondi, M., Batocchi, A. P., Coperchini, F., Caggiula, M., Zerbini, F., Sideri, R., Leporati, P., Nociti, V., Frisullo, G., Mirabella, M., Magri, F., Oliviero, A., Chiovato, L.. Severe disability in patients with relapsing-remitting multiple sclerosis is associated with profound changes in the regulation of leptin secretion. NeuroImmunoModulation. 2013; 20 (6): 341-347

    Kraszula, Ł., Jasińska, A., Eusebio, M.-O., Kuna, P., Głabiński, A., Pietruczuk, M.. Evaluation of the relationship between leptin, resistin, adiponectin and natural regulatory T cells in relapsing-remitting multiple sclerosis. Neurologia i Neurochirurgia Polska. 2012; 46 (1): 22-28

    Batocchi, A. P., Rotondi, M., Caggiula, M., Frisullo, G., Odoardi, F., Nociti, V., Carella, C., Tonali, P. A., Mirabella, M.. Leptin as a marker of multiple sclerosis activity in patients treated with interferon-beta. Journal of Neuroimmunology. 2003; 139 (1-2): 150-154

  • Related Organizations (3)
  • Metrics
Share - Bookmark