T-Cell Activation: A Queuing Theory Analysis at Low Agonist Density

Article, Other literature type English OPEN
Wedagedera, J. R.; Burroughs, Nigel John;

We analyze a simple linear triggering model of the T-cell receptor (TCR) within the framework of queuing theory, in which TCRs enter the queue upon full activation and exit by downregulation. We fit our model to four experimentally characterized threshold activation cri... View more
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