Pharmacological and neurobiological studies on Neuropeptide S and its receptor

Doctoral thesis Italian OPEN
Ruzza, Chiara;
(2011)
  • Publisher: Università degli studi di Ferrara
  • Subject: topi knockout per il recettore NPSR | Neuropeptide S | antagonisti NPSR | recettore del neuropeptide S | BIO/14 Farmacologia | risveglio | farmacologia in vitro e in vivo | NPSR antagonist | anxiety | in vitro and in vivo pharmacology | ansia | NPSR knockout mice | neuropeptide S receptor | arousal | BIO/14
    mesheuropmc: technology, industry, and agriculture

Neuropeptide S (NPS) is the last neuropeptide identified via reverse pharmacology techniques. NPS selectively binds and activates a previously orphan GPCR, now named NPSR, producing intracellular Ca2+ mobilization and stimulation of cAMP levels. Biological functio... View more
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