Efficiency of different strategies to mitigate ascertainment bias when using SNP panels in diversity studies

Article English OPEN
Dorcus Kholofelo Malomane; Christian Reimer; Steffen Weigend; Annett Weigend; Ahmad Reza Sharifi; Henner Simianer;
  • Publisher: BMC
  • Journal: BMC Genomics,volume 19 (issn: 1471-2164, eissn: 1471-2164)
  • Related identifiers: pmc: PMC5756397, doi: 10.1186/s12864-017-4416-9
  • Subject: Biotechnology | QH426-470 | Research Article | Ascertainment bias | SNP panels | Genetics | SNP filtering | LD based pruning | TP248.13-248.65

Background Single nucleotide polymorphism (SNP) panels have been widely used to study genomic variations within and between populations. Methods of SNP discovery have been a matter of debate for their potential of introducing ascertainment bias, and genetic diversity re... View more
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