A configuration space of homologous proteins conserving mutual information and allowing a phylogeny inference based on pair-wise Z-score probabilities

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Bastien, Olivier; Ortet, Philippe; Roy, Sylvaine; Maréchal, Eric;
  • Publisher: BMC
  • Journal: BMC Bioinformatics,volume 6,pages49-49 (issn: 1471-2105, eissn: 1471-2105)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC555736, doi: 10.1186/1471-2105-6-49
  • Subject: R858-859.7 | bioinformatique | Research Article | alignement de séquences | Computer applications to medicine. Medical informatics | SEQUENCE PROTEIQUE;METHODE AUTOMATIQUE | probabilité | protéine homologue | phylogénie | Biology (General) | QH301-705.5

<p>Abstract</p> <p>Background</p> <p>Popular methods to reconstruct molecular phylogenies are based on multiple sequence alignments, in which addition or removal of data may change the resulting tree topology. We have sought a representation of homologous proteins that ... View more
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