MDM2 binds and inhibits vitamin D receptor

Other literature type English OPEN
Heyne, Kristina; Heil, Tessa-Carina; Bette, Birgit; Reichrath, Jörg; Roemer, Klaus;
(2015)
  • Publisher: Taylor & Francis
  • Related identifiers: doi: 10.1080/15384101.2015.1044176, doi: 10.6084/m9.figshare.1412748, pmc: PMC4613177
  • Subject: Molecular Biology | transcription | Developmental Biology | vitamin D | Plant Biology | Extra View | Medicine | vitamin D receptor | MDM2 | tumor suppression | Hematology | Cell Biology | Genetics | Biochemistry | Pharmacology | Chemical Sciences not elsewhere classified | Cancer
    mesheuropmc: lipids (amino acids, peptides, and proteins) | polycyclic compounds | neoplasms | digestive, oral, and skin physiology

<p>The E3 ubiquitin ligase and transcriptional repressor MDM2 is a potent inhibitor of the p53 family of transcription factors and tumor suppressors. Herein, we report that vitamin D receptor (VDR), another transcriptional regulator and probably, tumor suppressor, is al... View more
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