Overproduction of α-Lipoic Acid by Gene Manipulated Escherichia coli.

Article English OPEN
Sun, Yirong; Zhang, Wenbin; Ma, Jincheng; Pang, Hongshen; Wang, Haihong;
(2017)
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE, volume 12, issue 1 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC5222372, doi: 10.1371/journal.pone.0169369
  • Subject: Molecular Biology | Research Article | Chromatographic Techniques | Antioxidants | Organosulfur Compounds | Oxidoreductases | Enzymes | DNA construction | Chemical Compounds | Artificial Gene Amplification and Extension | Physical Sciences | Molecular Biology Techniques | Proteins | Biosynthesis | Dehydrogenases | Lipoic Acids | Polymerase Chain Reaction | Chemistry | Biology and Life Sciences | Research and Analysis Methods | Liquid Chromatography | Medicine | Enzymology | Chemical Synthesis | Q | High Performance Liquid Chromatography | R | Biochemistry | Science | Plasmid Construction

Alpha-lipoic acid (LA) is an important enzyme cofactor widely used by organisms and is also a natural antioxidant for the treatment of pathologies driven by low levels of endogenous antioxidants. In order to establish a safer and more efficient process for LA production... View more
Share - Bookmark