Fibrinolytic activity is associated with presence of cystic media degeneration in aneurysms of the ascending aorta

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Gomez, Delphine; Borges, Luciano F.; Leclercq, Anne; Freymuller, Edna; Touat, Ziad; Meilhac, Olivier; Quintana, Mercedes; Vranckx, Roger; Gutierrez, Paulo S.; Michel, Jean-baptiste; Jandrot-perrus, Martine; Jondeau, Guillaume;

International audience; Aims Thoracic Ascending Aortic Aneurysms (TAA) are characterized by elastic fibre breakdown and cystic medial degeneration within the aortic media, associated with progressive SMC rarefaction. The TGF-β/Smad2 signaling pathway is involved in this... View more
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