Autoantibody to MDM2: A Potential Serological Marker of Systemic Lupus Erythematosus

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Liu, Yuan; Dai, Liping; Liu, Weihong; Shi, Guixiu; Zhang, Jianying;
  • Publisher: Hindawi Publishing Corporation
  • Journal: Journal of Immunology Research,volume 2,015 (issn: 2314-8861, eissn: 2314-7156)
  • Related identifiers: doi: 10.1155/2015/963568, pmc: PMC4451996
  • Subject: Research Article | Article Subject
    mesheuropmc: skin and connective tissue diseases | enzymes and coenzymes (carbohydrates) | immune system diseases | neoplasms

Introduction. Systemic lupus erythematosus (SLE) is one of the systemic autoimmune diseases characterized by the polyclonal autoantibody production. The human homologue of the mouse double minute 2 (MDM2) is well known as the negative regulator of p53. MDM2 has been rep... View more
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